Patients with dementia with Lewy bodies (DLB) may display a different cognitive pattern from Alzheimer's disease (AD) with more severe impairment performing visuospatial/visuoconstructive tasks. A commentary on Lawn and ffytche (2021), Functional Brain Connectivity Patterns Associated with Visual Hallucinations in Dementia with Lewy Bodies, Catatonia as Presenting Manifestation of Behavioral Frontotemporal Dementia: Insight From a PET/MRI Study, Being the Family Caregiver of a Patient With Dementia During the Coronavirus Disease 2019 Lockdown, Cerebellar and cortical hypometabolism in progressive stimulus-sensitive limb myoclonus in celiac disease, Changes of metabolic connectivity in dementia with Lewy bodies with visual hallucinations: a 18F-FDG PET/MR study, White matter abnormalities of right hemisphere attention networks contribute to visual hallucinations in dementia with Lewy bodies, Trazodone: a multifunctional antidepressant. The Italian dementia with lewy bodies study group (DLB-SINDEM): A multicenter survey on the accuracy and the prevalence of DLB diagnosis, Cortical network modularity changes along the course of frontotemporal and Alzheimer's dementing diseases, The functional role of cerebellum in visual hallucinations, Atypical Horton's arteritis with oculomotor nerves involvement and acute brain ischemic lesion: A case report, Late-onset affective and psychotic disorders: The challenge of disentangling neurodegenerative diseases from primary psychiatric disorders, Frontotemporal right predominant hypometabolism in bvFTD is not frequent and associated with more severe temporal atrophy. endobj
It covers the entire field of glial research from the basic molecular and cellular properties of these cells to their involvement in neurological diseases including stroke, Alzheimer's Disease, and multiple sclerosis. Recent evidence has demonstrated the efficacy of Virtual Reality (VR) for stroke rehabilitation nonetheless its benefits and limitations in large population of patients have not yet been studied. Posterior reversible encephalopathy syndrome (PRES) consists in a reversible subcortical vas... Cognitive and behavioral variables predicting behavioral frontotemporal dementia (bvFTD) versus primary psychiatric disorders mimicking bvFTD (phenocopy syndrome: bvFTD-PS) were studied. VH have been associated with cognitive alterations, although research findings in this area are still limited. These data motivate harmonized multicenter longitudinal cohort studies to improve clinical management a... An asymptomatic 74-year-old woman, on follow-up for a carotid body tumour, showed MRI focal restricted diffusion confined to the left temporal and occipital cortices. It addresses the question of whether microglia are . The present review summarises the current literature on the neural correlates of VH in LBD, namely Parkinson... Background: The Journal of Maternal-Fetal & Neonatal Medicine: Vol. Stefania Pezzoli 1 , Raquel Sánchez-Valle 2 , Aleix Solanes 3 , Matthew J Kempton 4 , Oliver Bandmann 5 , Jae Il Shin 6 , Annachiara Cagnin 7 , Jennifer G Goldman 8 , Doug Merkitch 8 , Michael J Firbank 9 , John-Paul Taylor 9 , Javier Pagonabarraga 10 , Jaime Kulisevsky 10 , Frederic Blanc 11 , Norma Verdolini 12 , Annalena Venneri 13 . Annachiara Cagnin: Drafting/revision of the manuscript for content, including medical writing for content Massimo Caulo: Drafting/revision of the manuscript for content, including medical writing for content Roxana Carare: Drafting/revision of the manuscript for content, including medical writing for content Feasibility and efficacy of cognitive telerehabilitation in early Alzheimer's disease: a pilot study Nela Jelcic,1 Michela Agostini,1 Francesca Meneghello,1 Cinzia Bussè,2 Sara Parise,2 Antonietta Galano,2 Paolo Tonin,1 Mauro Dam,1 Annachiara Cagnin1,2 1Foundation IRCCS San Camillo Hospital, Laboratory of Kinematics and Robotics and Laboratory of Psychology, Neurorehabilitation Department . pathy, preoperative, intraoperative, and perioperative blood components use, serum levels, and variation of Na+, Cl−, and K+ and immunosuppression were compared between CPM/EPM patients and control group of transplanted patients without neurologic complications. A 78-year-old woman complained of daytime recurrent VHs characterized by seeing her face and arms covered in fur and viewing moustaches on her daughter's face. 3 0 obj
The limitations of a binary classification of scans, the possibility to obtain early... Background: 28, No. In-vivo measurement of activated microglia in dementia. Results Among 997 transplants, CPM/EPM were diagnosed in 11 patients (1.1%), of whom four were CPM, one was EPM, and six were . Address: VIA GIUSTINIANI, 5 - PADOVA . Although some works have shown recovery of motor and cognitive function, including memory, attention, and executive functions, until today no studies have focused on language recovery after cranioplasty. n the human thalamus but not somatosensory cortex: these brain structures appeared morphologically normal on magnetic resonance imaging (MRI). © 2021 University of Padua - All rights reserved, Erasmus and other student Exchange Programmes, Coimbra Group - Student Exchange Network (SEN), European Credit Transfer and Accumulation System - ECTS, Healthcare and Primary Services for temporary stays, PATHOLOGY, NEUROLOGY AND PSYCHOPHARMACOLOGY, AA 2020 (MEP8085683), FUNCTIONAL REHABILITATION 2, AA 2019 (MEP3053074), MOTOR ACTIVITY FOR THE PREVENTION OF MUSCULOSKELETAL AND NEUROPSYCHIATRIC DISEASES AND THEIR COMPLICATION, AA 2018 (MEO2043411), FUNCTIONAL REHABILITATION 2, AA 2018 (MEP3053074), MOTOR ACTIVITY FOR THE PREVENTION OF MUSCULOSKELETAL AND NEUROPSYCHIATRIC DISEASES AND THEIR COMPLICATION, AA 2017 (MEO2043411), FUNCTIONAL REHABILITATION 2, AA 2017 (MEP3053074), CLINICAL PSYCHIATRY AND NEUROLOGY, AA 2016 (MEP3055883), FUNCTIONAL REHABILITATION 2, AA 2016 (MEP3053074), CLINICAL PSYCHIATRY AND NEUROLOGY, AA 2015 (MEP3055883), Certified mail: amministrazione.centrale@pec.unipd.it. Thursday, July 20, 2017: Focused Topic Session: FTS5-02: Advancing Health . Alessandro Salvalaggio, Annachiara Cagnin, Piero Marson, Franco Ferracci, Pietro Cortelli, Maurizio Corbetta, Chiara Briani Department of Neurology Division of Biology and Biomedical Sciences Objective: Our aim was to explore specific echogenic alterations of the SN in dementia with Lewy bodies (DLB) compared to Alzheimer's disease (AD). Annachiara Cagnin 9.45 Biomarkers Laura Bonanni 10.00 Management and therapy of behavioral disorders Marianna Amboni 10.15 Discussion ORAL COMMUNICATIONS Chairpersons: Andrea Arighi - Valentina Bessi 10.30 Physiotherapy with dual-tasks improves cognition in Parkinson's disease with postural instability and gait disorders Morphosyntactic production in Greek- and Italian-speaking individuals with probable Alzheimer's disease: Evidence from subject-verb agreement, tense/time reference, and mood. However, studies are still limited, especially investigating the resting-state functional brain features und... Background: Family caregivers of patients with dementia are at high risk of stress and burden, and quarantine due to the coronavirus disease 2019 (COVID-19) pandemic may have increased the risk of psychological disturbances in this population. Milena Zucca 1 , Valeria Isella 2 , Raffaele Di Lorenzo 3 , Camillo Marra 4 , Annachiara Cagnin 5 , Chiara Cupidi 6 , Laura Bonanni 7 , Valentina Laganà 3 , Elisa Rubino 8 , Nicola Vanacore 9 , Federica Agosta 10 11 12 , Paolo Caffarra 13 , Renato Sambati 14 15 , Davide Quaranta 4 , Valeria Guglielmi 4 , Ildebrando M Appollonio 2 , Giancarlo . Annachiara Cagnin Department of Neuroscience & Padova Neuroscience Center, University of Padova, Italy . https://www.hindawi.com/journals/np/si/926454/cfp/ We describe a patient with prodromal dementia with Lewy bodies (DLB) presenting with drug-induced visual hallucinations (VHs). Clusters of activated microglia occur only in complement-positive amyloidβ (Aβ) plaques, and effector functions of complement include the modulation of microglial activity in vitro. Caregiver stress and burden, often described as an "enduring stress and frustration" phenomenon (Butcher et al., 2001), may have an extremely heavy impact on lives of family members who take care of relatives with dementia.Caregiver stress is mainly characterized by psychological symptoms such as anxiety, depression, irritability, feelings of being overwhelmed or abandonment . The experience of lockdown leads to negative psychological outcomes for fragile people such as elderly with dementia, particu... Background: Background and Objectives Probable autoimmune encephalitis presenting with epilepsy, fever and ageusia: A possible COVID-19-related event? The current study was carried out during the national lockdown declared in March 2020 by the Italian gover... Background: Thursday, July 20, 2017: Featured Research Session: F5-03: Immunity and Alzheimer's Disease: Biological Mechanisms Underlying Genetic Risk. It has been proposed that VH arise from a disrupted organization of functional brain networks. Patients with Lewy body disease (LBD) frequently experience visual hallucinations (VH), well-formed images perceived without the presence of real stimuli. Alessandro Salvalaggio, Annachiara Cagnin, Piero Marson, Franco Ferracci, Pietro Cortelli, Maurizio Corbetta, Chiara Briani> ;Journal of Clinical Apheresis. Transcranial sonography (TCS) of the brain parenchyma detects alterations in the substantia nigra (SN), raphe nuclei, and basal ganglia; this technique has been established as a . Manuscript Due Friday, 31 March 2017 Severe hypernatremia may produce central pontine or extrapontine myelinolysis and neuronal damage, depending on the level and duration of hypernatremia and the rapidity of its onset.1Neuroimaging findings presented here demonstrate a selective vulnerability of the regions belonging to the limbic system network to the effects of an acute and extreme hypernatremia. Transcranial sonography (TCS) of the brain parenchyma is used to visualize alterations in the substantia nigra (SN) and it is applied for early diagnosis of Parkinson's disease. Electroencephalography (EEG) was recorded in 18 FTD and 18 AD patients at the prodromal stage of dementia, at dementia onset, and... Around half of the patients with GuillainâBarré syndrome (GBS) present autonomic dysfunction requiring admission to intensive care unit in up to a quarter of patients. This edition includes new chapters on transmitter release by extocytosis from glia, glia derived stem cells, glia . The role of 5-HT 3 receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice. Two earlier studies 2,3 reported test results of CSF and nasal brushings using a less refined RT-QuIC method on groups . The majority of neuroscientists now acknowledge that neuroglia are elemental to most, if not all, brain functions. endobj
Thirteen months later, diffusion-weighted images revealed a bilateral cortical ribbon sign involving all lobes. Patients with Lewy body disease (LBD) frequently experience visual hallucinations (VH), well-formed images perceived without the presence of real stimuli. The aim of this study was to investigate which clinical and neuropsychological characteristics are associated with VHs and their predictive value over a 1 year follow-up. The structural and functional brain mechanisms underlying VH in LBD are still unclear. Background The presence of recurrent complex visual hallucinations (VHs) is a core feature of dementia with Lewy bodies (DLB). It has been hypothesized that synuclein- and amyloid-pathology act synergistically aggravati... Peripherin (PRPH), a type III intermediate filament, assembles with neurofilaments in neurons of the peripheral nervous system, including lower motor neurons (LMN). Understanding its pathogenetic mechanisms is critical to properly implement disease-modifying strategies. Dementia with Lewy bodies (DLB) is a neurodegenerative disease characterized by cognitive, behavioral and motor symptoms and has a more challenging clinical management and poorer prognosis compared to other forms of dementia. Molecular studies have recently identified different mutations in the ubiquilin-2 (UBQLN2) gene as causative of a familial form of X-linked ALS, 90% penetrant in women. Objective: A 43-year-old woman presented with progressive left visual loss, gait impairment, and urinary incontinence. Previous studies showed that quarantine for pandemic diseases is associated with several psychological and medical effects. To develop a positron emission tomography (PET) ligand for imaging the 'peripheral benzodiazepine receptor' (PBR) in brain and elucidating the relationship between PBR and brain diseases, four analogues (4−7) of N-(2,5-dimethoxybenzyl)-N-(5-fluoro-2-phenoxyphenyl)acetamide (2) were synthesized and evaluated as ligands for PBR. Annachiara Cagnin, David J Brooks, Angus M Kennedy, Roger N Gunn, R Myers, Federico E Turkheimer, Terry Jones, and Richard B Banati. Contenuto trovato all'internoMarco Travaglio racconta come i SIGNORINI GRANDI LINGUE, giornalisti e opinionisti di chiara fama (e fame) hanno beatificato la peggior classe dirigente d’Europa. Basta dar loro la parola. Martin Rossor MD, FRCP. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease mainly involving cortical and spinal motor neurones. Acute psychological effects of quarantine in frail elderly subjects with special needs, such as patients with dementia, have been poo... We investigated in a longitudinal multicenter cohort study functional cortical connectivity changes along the course of frontotemporal dementia (FTD) and Alzheimer's disease (AD) from the prodromal stage of the diseases. Methods This chapter focuses on the contribution of activated microglia to the progression of Alzheimer's disease (AD) at various stages of the pathological cascade. In ictal psychosis with complex visual hallucinations (VHs), widespread functional changes of cortical networks have been suggested. Join ResearchGate to contact this researcher and connect with your scientific community. Patients: Recent evidence has demonstrated the efficacy of Virtual Reality (VR) for stroke rehabilitation nonetheless its benefits and limitations in large population of patients have not yet been studied. Innocenzo Rainero 15.00 New screening tools for remote neuropsychological assessment in the Covid-19 era Camillo Marra 15.20 ORAL COMMUNICATION 15.30-16.00 LECTURE Covid-19 and neuroinflammation with unrestricted grant by . - Biological factors promoting neural plasticity in people undergoing neurorehabilitation Objective: Nel libro vengono quindi proposti, attraverso i contributi dei massimi esperti di didattica inclusiva: – suggerimenti utili per impostare percorsi educativo-didattici realmente inclusivi e volti a promuovere il pieno apprendimento di ... Background. Journal article by Valantis Fyndanis, Dimitra Arfani, Spyridoula Varlokosta, Francesca Burgio, Anna Maculan, Gabriele Miceli, Giorgio Arcara, Fabio Palla, Annachiara . This study aims to validate this instrument in an European context, in particular in an Italian sample. Notwithstanding, in a number of cases with positive Visual hallucinations (VH) are common in dementia with Lewy bodies (DLB), and are among the core symptoms for its clinical diagnosis. Hippocampal subfield volumes were analyzed using . To study whether specific measures of verbal memory obtained with the Rey Auditory Verbal Learning test (RAVLT) could help distinguish dementia with Lewy bodies (DLB) from Alzheimer's... A novel neuronal tauopathy, mainly confined to hypothalamus and brainstem tegmentum, has recently been reported in patients with autoantibodies to the neuronal cell-adhesion molecule IgLON5. The aim of this study was to determine which characteristics could better distinguish dementia with Lewy bodies (DLB) from Alzheimer's disease (AD) at the mild cognitive impairment (MCI) stage, with particular emphasis on visual space and object perception abilities. Annachiara Cagnin. The present review summarises the current literature on the neural correlates of VH in LBD, namely Parkinson's disease (PD), and dementia with Lewy . Sporadic Creutzfeldt-Jakob disease (sCJD) is the commonest form of human prion diseases, accounting for about 85% of all cases. The presence of recurrent complex visual hallucinations (VHs) is a core feature of dementia with Lewy bodies (DLB). Time reference in agrammatic aphasia and probable Alzheimer�s disease: A cross-linguistic test of the PAst DIscourse LInking Hypothesis. Here, we aimed to review the main applications of TCS i... Background: In probable Alzheimerâs disease (AD), different memory systems, executive functioning, visuospatial recognition, and language are impaired. This book details the basic biology and function of glial cells. {tCpj����nZ��=`���-;>?dl5�j$�20:��Sr@���#ç.�U�g�mkڊ_�5���w���ʮa���?b���m�$�X��6)��m��@^��̮I)'?fE��'zl�8�]���j�tG"q��JϹq-;��������$2�&�"�/S��W�n�5��:���[��C����9����~��;,\`G7u-\%]]��1>�ɔ�� �߹��ym�X��}.��N�pQ�1�̇7A�[�2G�y�j>@�)kd��u L'emergenza Covid-19 ha contribuito ad evidenziare sempre di più l'estrema complessità del paziente psicogeriatrico in termini di salute (fragilità, disabilità, trattamento e comorbidità), esiti (Post Covid Syndrome, effetti centrali del virus, etc), criticità organizzative (ospedali, RSA e Rete . This multimodal MRI study aims at exploring structural and functional basis of VH. 2 0 obj
However, data on plasma lipoproteins cholesterol distribution and oxidation in AD and their possible genetic determinants are lacking. TY - JOUR T1 - Being the Family Caregiver of a Patient With Dementia During the Coronavirus Disease 2019 Lockdown. Although impairment of declarative memory is not considered a core feature of cognitive impairment in dementia with Lewy bodies (DLB) [], some aspects of episodic verbal memory, such as immediate or delayed free recall, may be compromised as severely as in Alzheimer's disease (AD) [].Some authors demonstrated that both DLB [] and AD patients [] performed worse than healthy . Show more profiles Show fewer profiles Erison's public profile badge Include this LinkedIn profile on other websites . The aim of our study was to analyse the UBQLN2 g... Mutations in the profilin 1 (PFN1) gene, encoding a protein regulating filamentous actin growth through its binding to monomeric G-actin, have been recently identified in familial amyotrophic lateral sclerosis (ALS). e-mail: annachiara.cagnin@unipd.it. Dr. ANNACHIARA CAGNIN- Short Curriculum Vitae Born 31 August 1967 in Verona (Italy) Italian citizenship CURRENT ADDRESS Neurology Clinic Neuroscience Department (DNS) Azienda Ospedaliera di Padova via Giustiniani 5, 35128 Padova (Italy) Email: annachiara.cagnin@unipd.it CURRENT ACADEMIC POSITION <>/ExtGState<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 595.32 841.92] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>>
Causative genes have been identified, with an autosomal dominant pattern of inheritance. Craniectomy, used to relieve refractory intracranial pressure in traumatic brain injury (TBI), may cause cognitive deficits which could be improved by skull breach repair. We conducted meta-analyses of voxel-based morphometry (VBM) and neuropsychological studies investigating the neuroanatomical and cognitive correlates o... Dementia with Lewy bodies (DLB) is a neurodegenerative disease characterized by cognitive, behavioral and motor symptoms and has a more challenging clinical management and poorer prognosis compared to other forms of dementia. Contenuto trovato all'internoQuesta sesta edizione del Nelson Manuale di Pediatria, alla quale hanno collaborato per ogni tema specialistico alcune tra le figure più eminenti della pediatria internazionale, tratta in modo sintetico e chiaro una materia ampia e ...